The BNP test alone was more accurate than any history or physical exam finding in predicting CHF as the cause of dyspnea. One must remember that BNP has a range of NPV and PPV depending on the value and you shouldn’t use a single cut point in making clinical decisions.
Reference:
Breathing Not Properly Study: N Engl J Med 2002; 347:161-167 http://www.nejm.org/doi/full/10.1056/NEJMoa020233#t=abstract